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Phospho-PFKFB2-S483 pAb

Catalog # Availability Size / Price Inquiry
AMR01067N-1 50ul / $395
AMR01067N-2 100ul / $495
AMR01067N-3 200ul / $595

Phospho-PFKFB2-S483 pAb

Brand

Leading Biology

Catalog Number

AMR01067N

Product Type

Phosphorylated Antibodies

Field of Research

Endocrine & Metabolism>Carbohydrate metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-PFKFB2-S483 pAb.

Molecular Weight

Calculated MW: 54kDa/58kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around S483 of human PFKFB2 (NP_006203.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IP

Dilution

WB 1:500 - 1:2000 IP 1:50 - 1:100

Product Description

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Synonyms

PFKFB2; PFK-2/FBPase-2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Images

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Specification

Quantity

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