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Phospho-FLNA-S2152 pAb

Catalog # Availability Size / Price Inquiry
AMR01066N-1 50ul / $395
AMR01066N-2 100ul / $495
AMR01066N-3 200ul / $595

Phospho-FLNA-S2152 pAb

Brand

Leading Biology

Catalog Number

AMR01066N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-FLNA-S2152 pAb.

Molecular Weight

Calculated MW: 280kDa Observed MW: 300kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around S2152 of human FLNA (NP_001104026.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

FLNA; ABP-280; ABPX; CSBS; CVD1; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD; filamin-A

Images

Western blot analysis of extracts of HeLa and C6 cells, using Phospho-FLNA-S2152 antibody.

Specification

Quantity

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