Introduction

With the world-leading capacity, Leading Biology is able to provide a pre-made library sequencing service at highly competitive and cost-effective prices. We have developed a comprehensive library screening strategy for efficient isolation of high affinity antibodies from both yeast and phage libraries.

For the rapid turnaround and consistent results for your projects, we also provide the in-stock premade human and mouse antibody libraries (including human scFv libraries, human Fab libraries, mouse scFv/Fab libraries, rabbit Fab libraries, chicken scFv libraries and single domain antibody libraries) with great capacity & diversity that can derive high affinity antibodies ranging from 10 pM to 10 nM.

HuScL-2: Human Single Chain Antibody Library

1.     Phagemid phage display system

2.     M13 pIII fusion containing short 6xHis and c-Myc detection tag

3.     VH-VL format scFv library

4.     Human antibody genes from semi-synthesis

5.     Capacity: 1.42×10⁹

6.     Proliferation in TG1 cells

7.     Production of soluble antibody fragments in HB2151

8.     Helper phage KM13

HuFabL-1: Human Fab Antibody Library

1.     Phagemid phage display system

2.     M13 pIII fusion containing short 6xHis and c-Myc detection tag

3.     Fab format

4.     Human antibody genes for high-throughput screening.

5.     Capacity: 2.0×10⁹

6.     Proliferation in TG1 cells

7.     Production of soluble antibody fragments in HB2151

8.     Helper phage M13K07

Alpaca Single Chain Antibody Library
1.     Phagemid phage display system
2.     M13 pIII fusion containing short 6xHis and c-Myc detection tag
3.     VH-VL format scFv library
4.     Alpaca antibody genes derived from none immunized alpaca
5.     Capacity: 1*10^9
6.     Proliferation in TG1 cells

Besides, we are currently working on the construction and validation of several Fab synthetic libraries using Trimer Codon technology, which has natural diversity and favorable biophysical properties.

Why Leading Biology?

We offer the one-stop phage display service:

•      Immune, naive or synthetic library construction
•      Pre-made library screening
•      Monoclonal detection
•      Antibody expression
•      Custom biopanning strategies
•      QC: to ensure the success of your projects, we perform documentation QC for all assays.

Our advantages

•      World-leading sequencing capacity: use state-of-the-art technologies, such as Timer Condon technology, nanopore platform, etc with library capacity from 10⁸ to over 10¹¹ ;
•      Various phage display systems: provide the most appropriate phage display system (M13, T4 or T7) to meet our customers’ demands.
•       High affinity: from 10^-7 to 10^-9
•      Custom biopanning strategies: The experienced technical team will work together to customize our products so as to meet our customers’ different needs. Leading Biology also utilizes the novel biopanning strategies to select high-affinity binders or ligands which are able to recognize the naive targets. Our Naive human antibody library panning includes: Pre-made yeast display naive human antibody library & Pre-made phage display naive human Fab library.
•      Rich experience: Our technicians refine every detail of our processing to enable the efficiency and high-quality. With extensive experience in phage display, we have provided satisfying service to our global researchers.

Contact US

We are proud to be able to support global scientists by providing high-quality service in a rapid time-frame. Reach out to us and we will get back to you within 24 hours.

Get a free quote

Email: info@leadingbiology.com

Phone: 1-661-524-0262 (USA)