> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UNC13B Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR22357N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Apoptosis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UNC13B Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
180kDa/182kDa
Observed MW:
210kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human UNC13B (NP_006368.3).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
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Synonyms |
UNC13B; MUNC13; UNC13; Unc13h2; unc-13 homolog B
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Images |
Western blot analysis of extracts of various cell lines, using UNC13B antibody. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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