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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Factor IX / F9 Polyclonal Antibody

Factor IX / F9 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22356N-1 50ul / $395
APR22356N-2 100ul / $495
APR22356N-3 200ul / $595

Factor IX / F9 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22356N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Factor IX / F9 Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa/51kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Factor IX / F9 (NP_000124.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Synonyms

F9; F9 p22; FIX; HEMB; P19; PTC; THPH8; F9p22; coagulation factor IX

Images

Western blot analysis of extracts of various cell lines, using Factor IX / F9 antibody.

Immunofluorescence analysis of rat liver using Factor IX / F9 Polyclonal Antibody.

Immunofluorescence analysis of human placenta using Factor IX / F9 Polyclonal Antibody.

Specification

Quantity

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