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GLI3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22183N-1 50ul / $395
APR22183N-2 100ul / $495
APR22183N-3 200ul / $595

GLI3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22183N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Hedgehog Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLI3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 169kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human GLI3 (NP_000159.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.

Synonyms

GLI3; ACLS; GCPS; GLI3-190; GLI3FL; PAP-A; PAPA; PAPA1; PAPB; PHS; PPDIV; GLI family zinc finger 3

Images

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Specification

Quantity

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