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MKKS Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21893N-1 50ul / $395
APR21893N-2 100ul / $495
APR21893N-3 200ul / $595

MKKS Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21893N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MKKS Polyclonal Antibody.

Molecular Weight

Calculated MW: 62kDa Observed MW: 62kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MKKS (NP_740754.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.

Synonyms

MKKS; BBS6; HMCS; KMS; MKS; McKusick-Kaufman syndrome

Images

Western blot analysis of extracts of K-562 cells, using MKKS antibody.

Specification

Quantity

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