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PTP4A2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21892N-1 50ul / $395
APR21892N-2 100ul / $495
APR21892N-3 200ul / $595

PTP4A2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21892N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTP4A2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 9kDa/15kDa/16kDa/19kDa Observed MW: 19kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PTP4A2 (NP_536316.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:200 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Synonyms

PTP4A2; HH13; HH7-2; HU-PP-1; OV-1; PRL-2; PRL2; PTP4A; PTPCAAX2; ptp-IV1a; ptp-IV1b; protein tyrosine phosphatase type IVA 2

Images

Western blot analysis of extracts of various cell lines, using PTP4A2 antibody.

Specification

Quantity

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