> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NT3 AntibodyBrand |
Leading Biology | Catalog Number |
AMM06838G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NT3 antibody.
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Molecular Weight |
29355 Da
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Peptide GEIKTGNSPV(C),??corresponding to amino acid residues 39-48 of mature human NT-3??(residues 177-186 of the NT-3 precursor) (Accession P20783).
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GeneID |
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UniProt ID |
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Summary |
The neurotrophins ("neuro" means nerve and "trophe" means nutrient) are a family of soluble,basic growth factors which regulate neuronal development, maintenance, survival and death in the CNS and the PNS.1 The structural hallmark of all the neurotrophins is the characteristicarrangement of the disulfide bridges known as the cysteine knot, which has been found in othergrowth factors such as PDGF.2 The rat and human forms of Neurotrophin-3 (NT-3) are 96% homologous. NT-3 has been shown to strengthen synaptic connections to motoneurons in the neonatal rat,3to serve as an anti-inflammatory factor, to suppress microglial activation,4 to play a criticalrole in regulating T helper 1/T helper 2 cell balance5 and to modify potassium currents in isolated inner hair cells from guinea pig cochlea.6 The biological effects of NT-3 are mediatedby two receptors: TrkC, which is specific for NT-3, and p75NTR, which binds all the neurotrophins.7
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Form |
Affinity purified antibody, Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Dilution |
WB~~1:200-1:2000
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Synonyms |
Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor, NTF3
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Images |
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Specification |
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Quantity |
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| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
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| 3 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
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| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask | ||
| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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