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TENM3 Antibody

Catalog # Availability Size / Price Inquiry
APR13726G 0.1 mg / $695

TENM3 Antibody

Brand

Leading Biology

Catalog Number

APR13726G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TENM3 antibody.

Molecular Weight

Predicted: 297 kDa Observed: 300 kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass membrane protein. Cell projection, axon

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

TENM3; TENM3 antibody is human, mouse and rat reactive. TENM3 antibody is predicted to not cross-react with other members of the TENM family.

Isotype

IgG

Symbol

KIAA1455, ODZ3, TNM3

GeneID

UniProt ID

Function

Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes axon guidance and homophilic cell adhesion. Plays a role in the development of the visual pathway; regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. May function as a cellular signal transducer (By similarity).

Summary

The teneurin transmembrane protein 3 (TENM3) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM3 is expressed in cartilaginous cells during postnatal growth in mice (3), as well as the adult eye and optic stalk (4). Homozygous null mutations in TENM3 causes microphthalmia in humans (5).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of TENM3 in 293 cell lysate with TENM3 antibody at 1 μg/ml.

Immunohistochemistry of TENM3 in mouse brain tissue with TENM3 antibody at 5 μg/mL.

Immunofluorescence of TENM3 in mouse brain tissue with TENM3 antibody at 20 μg/mL.

Specification

Quantity

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