> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TENM1 AntibodyBrand |
Leading Biology | Catalog Number |
APR13725G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TENM1 antibody.
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Molecular Weight |
Predicted: 301 kDa Observed: 280 kDa
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass membrane protein Teneurin C-terminal-associated peptide: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with the dystroglycan complex at the cell membrane in hippocampal cells. Binds hippocampal cell membranes and is incorporated in the cytoplasm by endocytosis in a caveoli-dependent manner. Upon cell internalization is transported arround and in the nucleus (By similarity).
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
TENM1; TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family.
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Isotype |
IgG
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Symbol |
ODZ1, TNM1
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GeneID |
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UniProt ID |
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Function |
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer (By similarity).
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Summary |
The teneurin transmembrane protein 1 (TENM1) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM1 is expressed primarily in the developing central nervous system and may be proteolytically cleaved with the intracellular domain translocating to the nucleus (3). TENM1 is a direct target of the homeobox transcription factor EMX2, a transcription factor thought to be important for area specification in the developing cortex (4).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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