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Polyclonal Antibodies >
TMEM70 AntibodyBrand |
Leading Biology | Catalog Number |
APR10491G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TMEM70 antibody.
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Molecular Weight |
28969 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
TMEM70;
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Function |
Involved in biogenesis of mitochondrial ATP synthase.
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Summary |
TMEM70 Antibody: TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
Western blot analysis of TMEM70 in human liver tissue lysate with TMEM70 antibody at 1 μg/mL. Immunohistochemistry of TMEM70 in rat liver tissue with TMEM70 antibody at 5 μg/mL. Immunofluorescence of TMEM70 in rat liver tissue with TMEM70 antibody at 20 μg/mL. |
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Specification |
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Quantity |
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