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LRRC19 Antibody

Catalog # Availability Size / Price Inquiry
APR17237G 0.1 mg / $695

LRRC19 Antibody

Brand

Leading Biology

Catalog Number

APR17237G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LRRC19 antibody.

Molecular Weight

42334 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

LRRC19;

Isotype

IgG

GeneID

UniProt ID

Summary

LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of LRRC19 in K562 cell lysate with LRRC19 antibody at 1 μg/mL.

Immunocytochemistry of LRCC19 in K562 cells with LRCC19 antibody at 2.5 μg/mL.

Specification

Quantity

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