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GRASP Antibody

Catalog # Availability Size / Price Inquiry
APR12244G 100 μl / $545

GRASP Antibody

Brand

Leading Biology

Catalog Number

APR12244G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRASP antibody.

Molecular Weight

95 KDa

Host

Rabbit

Species Reactivity

Rat

Target

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

GeneID

UniProt ID

Summary

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).

Form

Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the C-terminal peptide used as antigen.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:1000

Synonyms

GRIP1-associated protein 1, GRASP-1, Gripap1, Grasp1

Images

Western blot of rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein.

Specification

Quantity

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