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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Amyloid Precursor Protein Antibody

Amyloid Precursor Protein Antibody

Catalog # Availability Size / Price Inquiry
APR11408G 100 μl / $545

Amyloid Precursor Protein Antibody

Brand

Leading Biology

Catalog Number

APR11408G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Amyloid Precursor Protein antibody.

Molecular Weight

115 KDa

Host

Rabbit

Species Reactivity

Rat

Target

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

GeneID

UniProt ID

Summary

A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimer's disease (AD) (Kamenetz et al., 2003). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD (Liu et al., 2003; Ando et al., 2001).

Form

Prepared from rabbit serum by affinity purification on a column made with the C-terminal peptide used as antigen

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:1000

Synonyms

Amyloid beta A4 protein, ABPP, APP, Alzheimer disease amyloid A4 protein homolog, Amyloidogenic glycoprotein, AG, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Gamma-CTF(50), C31, App

Images

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115k APP protein.

Specification

Quantity

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