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SYN3 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR13606G 100 μl / $495

SYN3 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR13606G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SYN3 antibody (Center).

Molecular Weight

63303 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles

Host

Rabbit

Species Reactivity

Human

Immunogen

363-388 aa

Target

This SYN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-388 amino acids from the Central region of human SYN3.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May be involved in the regulation of neurotransmitter release and synaptogenesis.

Summary

This gene is a member of the synapsin gene family.Synapsins encode neuronal phosphoproteins which associate with thecytoplasmic surface of synaptic vesicles. Family members arecharacterized by common protein domains, and they are implicated insynaptogenesis and the modulation of neurotransmitter release,suggesting a potential role in several neuropsychiatric diseases.The protein encoded by this gene shares the synapsin family domainmodel, with domains A, C, and E exhibiting the highest degree ofconservation. The protein contains a unique domain J, locatedbetween domains C and E. Based on this gene's localization to22q12.3, a possible schizophrenia susceptibility locus, and theestablished neurobiological roles of the synapsins, this familymember may represent a candidate gene for schizophrenia. The TIMP3gene is located within an intron of this gene and is transcribed inthe opposite direction.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Synapsin-3, Synapsin III, SYN3

Images

SYN3 Antibody (Center) (Cat. APR13606G) western blot analysis in NCI-H460 cell line lysates (15ug/lane).This demonstrates the SYN3 antibody detected the SYN3 protein (arrow).

SYN3 Antibody (Center) (Cat. APR13606G) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SYN3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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