> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > APG10L Antibody (C-term S116)Brand |
Leading Biology | Catalog Number |
APG01908G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality APG10L antibody (C-term S116).
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Molecular Weight |
25279 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
96-121 aa
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Target |
This APG10L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-121 amino acids from the C-terminal region of human APG10L.
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Isotype |
Rabbit Ig
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Symbol |
APG10L
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GeneID |
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UniProt ID |
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Function |
E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.
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Summary |
Autophagy is a process for the bulk degradation ofcytosolic compartments by lysosomes. ATG10 is an E2-like enzymeinvolved in 2 ubiquitin-like modifications essential forautophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261)conjugation and modification of a soluble form of MAP-LC3(MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to amembrane-bound form (Nemoto et al., 2003 [PubMed12890687]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Ubiquitin-like-conjugating enzyme ATG10, 632-, Autophagy-related protein 10, APG10-like, ATG10, APG10L
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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