> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > STC2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM08001G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality STC2 antibody (C-term).
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Molecular Weight |
33249 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Mouse
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Immunogen |
273-302 aa
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Target |
This STC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the C-terminal region of human STC2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
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Summary |
This gene encodes a secreted, homodimeric glycoproteinthat is expressed in a wide variety of tissues and may haveautocrine or paracrine functions. The encoded protein has 10 of its15 cysteine residues conserved among stanniocalcin family membersand is phosphorylated by casein kinase 2 exclusively on its serineresidues. Its C-terminus contains a cluster of histidine residueswhich may interact with metal ions. The protein may play a role inthe regulation of renal and intestinal calcium and phosphatetransport, cell metabolism, or cellular calcium/phosphatehomeostasis. Constitutive overexpression of human stanniocalcin 2in mice resulted in pre- and postnatal growth restriction, reducedbone and skeletal muscle growth, and organomegaly. Expression ofthis gene is induced by estrogen and altered in some breastcancers.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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