> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > B3GNT1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APG02154G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality B3GNT1 antibody (C-term).
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Molecular Weight |
47119 Da
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Cellular Localization |
Antigen Cellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Localizes near the trans-Golgi apparatus.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
366-394 aa
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Target |
This B3GNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-394 amino acids from the C-terminal region of human B3GNT1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Beta-1,4-glucuronyltransferase involved in O- mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O- mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha- dystroglycan (DAG1) (By similarity).
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Summary |
This gene encodes a member of thebeta-1,3-N-acetylglucosaminyltransferase family. This enzyme is atype II transmembrane protein. It is essential for the synthesis ofpoly-N-acetyllactosamine, a determinant for the blood group iantigen.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Beta-1, 4-glucuronyltransferase 1, 241-, I-beta-1, 3-N-acetylglucosaminyltransferase, iGnT, N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 1, B3GNT1 (HGNC:15685)
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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