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Polyclonal Antibodies >
GLYAT Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM04815G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GLYAT antibody (Center).
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Molecular Weight |
33924 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
171-199 aa
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Target |
This GLYAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human GLYAT.
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Isotype |
Rabbit Ig
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Symbol |
ACGNAT, CAT, GAT
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GeneID |
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UniProt ID |
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Function |
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
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Summary |
The glycine-N-acyltransferase protein conjugates glycinewith acyl-CoA substrates in the mitochondria. The protein isthought to be important in the detoxification of endogenous andxenobiotic acyl-CoA's. Two transcript variants encoding differentisoforms have been found for this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Glycine N-acyltransferase, Acyl-CoA:glycine N-acyltransferase, AAc, Aralkyl acyl-CoA N-acyltransferase, Aralkyl acyl-CoA:amino acid N-acyltransferase, Benzoyl-coenzyme A:glycine N-acyltransferase, Glycine N-benzoyltransferase, HRP-1(CLP), GLYAT, ACGNAT, CAT, GAT
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Images |
GLYAT Antibody (Center) (Cat. AMM04815G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GLYAT antibody detected the GLYAT protein (arrow). GLYAT Antibody (Center) (Cat. AMM04815G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GLYAT Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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