> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SSH3 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07985G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SSH3 antibody (C-term).
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Molecular Weight |
72996 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Nucleus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
575-602 aa
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Target |
This SSH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the C-terminal region of human SSH3.
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Isotype |
Rabbit Ig
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Symbol |
SSH3L
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GeneID |
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UniProt ID |
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Function |
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).
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Summary |
The ADF (actin-depolymerizing factor)/cofilin family (seeMIM 601442) is composed of stimulus-responsive mediators of actindynamics. ADF/cofilin proteins are inactivated by kinases such asLIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears toplay a role in actin dynamics by reactivating ADF/cofilin proteinsin vivo (Niwa et al., 2002 [PubMed 11832213]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, IF, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
IF~~1:10~50
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Synonyms |
Protein phosphatase Slingshot homolog 3, SSH-like protein 3, SSH-3L, hSSH-3L, SSH3, SSH3L
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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