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HIP1R Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR12376G 100 μl / $495

HIP1R Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR12376G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HIP1R antibody (N-term).

Molecular Weight

119388 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane Note=Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region

Host

Rabbit

Species Reactivity

Human

Immunogen

98-126 aa

Target

This HIP1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human HIP1R.

Isotype

Rabbit Ig

Symbol

HIP12, KIAA0655

GeneID

UniProt ID

Function

Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

Summary

This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Huntingtin-interacting protein 1-related protein, HIP1-related protein, Huntingtin-interacting protein 12, HIP-12, HIP1R, HIP12, KIAA0655

Images

HIP1R Antibody (N-term) (Cat. APR12376G) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HIP1R antibody detected the HIP1R protein (arrow).

HIP1R Antibody (N-term) (Cat. APR12376G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HIP1R Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

HIP1R Antibody (N-term) (Cat. APR12376G) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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