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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant

AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant

Catalog # Availability Size / Price Inquiry
APR07207G 0.1 ml / $395

AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant

Brand

Leading Biology

Catalog Number

APR07207G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMACR / p504S (Prostate Cancer Marker) antibody - Culture Supernatant .

Molecular Weight

54kDa

Cellular Localization

Antigen Cellular Localization: Peroxisome. Mitochondrion

Host

Rabbit

Species Reactivity

Human

Target

Full length human recombinant AMACR protein

Clone

13H4

Isotype

IgG

GeneID

UniProt ID

Function

Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.

Summary

This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

Form

0.5 ml of Culture Supernatant with azide

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Synonyms

Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR

Images

Formalin-fixed, paraffin-embedded human prostate carcinoma (10X) stained with AMACR / p504S Rabbit MAb (13H4).

Formalin-fixed, paraffin-embedded human prostate carcinoma (20X) stained with AMACR / p504S Rabbit MAb (13H4).

Specification

Quantity

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