> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Synapsin II AntibodyBrand |
Leading Biology | Catalog Number |
APR13612G |
Product Type |
Monoclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Synapsin II antibody.
|
||
Molecular Weight |
62847 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Cell junction, synapse.
|
||
Host |
Rabbit
|
||
Species Reactivity |
Human, Mouse, Rat
|
||
Target |
A synthetic peptide corresponding to residues in human Synapsin II was used as an immunogen.
|
||
Clone |
EPR3277
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons (By similarity).
|
||
Summary |
The synapsins are a family of at least five proteins that are specifically associated with the cytoplasmic surface of synaptic vesicles (1, 2). They are neuron-specific phosphoproteins that selectively bind to small synaptic vesicles in the presynaptic nerve terminal (3). The synapsins are implicated in neurotransmitter release and synaptogenesis, processes believed to be aberrant in several neuropsychiatric diseases (1). Synapsin II has been reported to specifically be involved in the formation and maintenance of synapses in hippocampal neurons (4). It has also been found to play a distinct role in neuronal development, as a study reported that the deletion of synapsin II greatly retarded axon formation, and the deletion of synapsin I retarded synapse formation (5). Synapsin II was furthermore suggested to participate in cytoskeletal organization during the early stages of nerve cell development (6).
|
||
Form |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, IHC, IF
|
||
Dilution |
WB~~1:5000~10000
IHC~~1:100~250
|
||
Synonyms |
Synapsin-2, Synapsin II, SYN2
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APG02467G | CCK4 / PTK7 Antibody (clone 4F9) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | AMM04683G | GALT Antibody (clone 4C11) | 50 μg | Monoclonal Antibodies |
|
$545.00 | Add Ask | ||
| 3 | Leading Biology | AMM01402G | Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
| 4 | Leading Biology | APR08280G | LTA4H / LTA4 Antibody (clone 9G8) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | AMM00172G | CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
| 6 | Leading Biology | AMM05750G | CEBPA Antibody | 100 μl | Monoclonal Antibodies |
|
$545.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
