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VEGFC Antibody

Catalog # Availability Size / Price Inquiry
APR04570G 100 μl / $495

VEGFC Antibody

Brand

Leading Biology

Catalog Number

APR04570G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VEGFC Antibody.

Molecular Weight

46883 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Target

This VEGFC antibody is generated from rabbits immunized with VEGFC recombinant protein.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Summary

VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Images

VEGFC Antibody (Cat. APR04570G) western blot analysis in 293T cell lysate (35ug/lane). This demonstrates that the VEGFC antibody detected VEGFC protein (arrow).

Western blot analysis of VEGFC Antibody (Cat. APR04570G) in 293 cell line lysates (35ug/lane). VEGFC (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with VEGFC Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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