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LALBA Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR04025G 100 μl / $495

LALBA Antibody (Center)

Brand

Leading Biology

Catalog Number

APR04025G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LALBA Antibody (Center).

Molecular Weight

16225 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

39-68 aa

Target

This LALBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human LALBA.

Isotype

Rabbit Ig

Symbol

LYZL7

GeneID

UniProt ID

Function

Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

Summary

This gene encodes alpha-lactalbumin, a principal proteinof milk. Alpha-lactalbumin forms the regulatory subunit of thelactose synthase (LS) heterodimer and beta1,4-galactosyltransferase (beta4Gal-T1) forms the catalyticcomponent. Together, these proteins enable LS to produce lactose bytransfering galactose moieties to glucose. As a monomer,alpha-lactalbumin strongly binds calcium and zinc ions and maypossess bactericidal or antitumor activity. A folding variant ofalpha-lactalbumin, called HAMLET, likely induces apoptosis in tumorand immature cells.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P~~1:10~50 WB~~1:1000

Images

APR04025G staining LALBA in Human breast tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.

Anti-LALBA Antibody (Center)at 1:2000 dilution + human breast lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 16 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Anti-LALBA Antibody (Center)at 1:2000 dilution + human breast lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 16 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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