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TGFBRAP1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03814G 100 μl / $495

TGFBRAP1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03814G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGFBRAP1 Antibody (C-term).

Molecular Weight

97158 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Note=Colocalizes with TGF-beta receptors in the absence of signaling

Host

Rabbit

Species Reactivity

Human

Immunogen

499-528 aa

Target

This TGFBRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human TGFBRAP1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.

Summary

TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

TGFBRAP1 Antibody (C-term) (Cat. APR03814G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TGFBRAP1 antibody detected the TGFBRAP1 protein (arrow).

TGFBRAP1 Antibody (C-term) (Cat. APR03814G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFBRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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