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POSTN Antibody (C-term)

APR03640G Product Datasheet Protocol

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APR03640G		100 μl / $495

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Leading Biology Inc.

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POSTN Antibody (C-term)

Brand	Leading Biology	Catalog Number	APR03640G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POSTN Antibody (C-term).
Molecular Weight	93314 Da
Cellular Localization	Antigen Cellular Localization: Golgi apparatus. Secreted, extracellular space, extracellular matrix. Note=Colocalizes with BMP1 in the Golgi.
Host	Rabbit
Species Reactivity	Human
Immunogen	687-716 aa
Target	This POSTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 687-716 amino acids from the C-terminal region of human POSTN.
Isotype	Rabbit Ig
Symbol	OSF2
GeneID	10631
UniProt ID	Q15063
Function	Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
Summary	POSTN binds to heparin. It induces cell attachment and spreading and plays a role in cell adhesion and may play a role in extracellular matrix mineralization.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, IF, E
Dilution	WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50
Images	POSTN Antibody (C-term) (Cat. APR03640G) western blot analysis in MCF-7(lane 1),A375(lane 2) cell line lysates (35ug/lane).This demonstrates the POSTN antibody detected the POSTN protein (arrow). POSTN Antibody (C-term) (Cat. APR03640G)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POSTN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Confocal immunofluorescent analysis of POSTN Antibody (C-term)( APR03640G) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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