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Primary Antibody >
Polyclonal Antibodies >
VEGF3 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03638G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VEGF3 Antibody (N-term).
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Molecular Weight |
46883 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
20-49 aa
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Target |
This VEGF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human VEGF3.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
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Summary |
The protein encoded by this gene is a member of theplatelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family, is active in angiogenesis and endothelial cellgrowth, and can also affect the permeability of blood vessels.This secreted protein undergoes a complex proteolytic maturation,generating multiple processed forms which bind and activate VEGFR-3receptors. Only the fully processed form can bind and activateVEGFR-2 receptors. This protein is structurally and functionallysimilar to vascular endothelial growth factor D. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Images |
Anti-VEGF3 Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST. VEGF3 Antibody (N-term) (Cat. APR03638G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the VEGF3 antibody detected the VEGF3 protein (arrow). VEGF3 Antibody (N-term) (Cat. APR03638G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VEGF3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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