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VEGF3 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR03638G 100 μl / $495

VEGF3 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR03638G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VEGF3 Antibody (N-term).

Molecular Weight

46883 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

20-49 aa

Target

This VEGF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human VEGF3.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Summary

The protein encoded by this gene is a member of theplatelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family, is active in angiogenesis and endothelial cellgrowth, and can also affect the permeability of blood vessels.This secreted protein undergoes a complex proteolytic maturation,generating multiple processed forms which bind and activate VEGFR-3receptors. Only the fully processed form can bind and activateVEGFR-2 receptors. This protein is structurally and functionallysimilar to vascular endothelial growth factor D. [provided byRefSeq].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

Anti-VEGF3 Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

VEGF3 Antibody (N-term) (Cat. APR03638G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the VEGF3 antibody detected the VEGF3 protein (arrow).

VEGF3 Antibody (N-term) (Cat. APR03638G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VEGF3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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