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SCEL Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03578G 100 μl / $495

SCEL Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03578G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCEL Antibody (Center).

Molecular Weight

77552 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Membrane. Note=May become cross- linked to membrane proteins by transglutaminase

Host

Rabbit

Species Reactivity

Human

Immunogen

260-289 aa

Target

This SCEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-289 amino acids from the Central region of human SCEL.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope.

Summary

The protein encoded by this gene is a precursor to thecornified envelope of terminally differentiated keratinocytes. Thisprotein localizes to the periphery of cells and may function in theassembly or regulation of proteins in the cornified envelope.Transcript variants encoding different isoforms exist. A transcriptvariant utilizing an alternative polyA signal has been described inthe literature, but its full-length nature has not been determined.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Images

SCEL Antibody (Center) (Cat. APR03578G) western blot analysis in NCI-H292,A549 cell line lysates (35ug/lane).This demonstrates the SCEL antibody detected the SCEL protein (arrow).

SCEL Antibody (Center) (Cat. APR03578G) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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