> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > COL1A2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03577G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality COL1A2 Antibody (N-term).
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Molecular Weight |
129314 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
16-43 aa
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Target |
This COL1A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human COL1A2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Type I collagen is a member of group I collagen (fibrillar forming collagen).
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Summary |
This gene encodes the pro-alpha2 chain of type I collagenwhose triple helix comprises two alpha1 chains and one alpha2chain. Type I is a fibril-forming collagen found in most connectivetissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfectatypes I-IV, Ehlers-Danlos syndrome type VIIB, recessiveEhlers-Danlos syndrome Classical type, idiopathic osteoporosis, andatypical Marfan syndrome. Symptoms associated with mutations inthis gene, however, tend to be less severe than mutations in thegene for the alpha1 chain of type I collagen (COL1A1) reflectingthe different role of alpha2 chains in matrix integrity. Threetranscripts, resulting from the use of alternate polyadenylationsignals, have been identified for this gene. [provided by R.Dalgleish].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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