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BCLAF1 Antibody (C-term)

APR03510G Product Datasheet Protocol

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APR03510G		100 μl / $495

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Leading Biology Inc.

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BCLAF1 Antibody (C-term)

Brand	Leading Biology	Catalog Number	APR03510G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BCLAF1 Antibody (C-term).
Molecular Weight	106122 Da
Cellular Localization	Antigen Cellular Localization: Cytoplasm. Nucleus.
Host	Rabbit
Species Reactivity	Human
Immunogen	658-687 aa
Target	This BCLAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1.
Isotype	Rabbit Ig
Symbol	BTF, KIAA0164
GeneID	9774
UniProt ID	Q9NYF8
Function	Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Summary	This gene encodes a transcriptional repressor thatinteracts with several members of the BCL2 family of proteins.Overexpression of this protein induces apoptosis, which can besuppressed by co-expression of BCL2 proteins. The protein localizesto dot-like structures throughout the nucleus, and redistributes toa zone near the nuclear envelope in cells undergoing apoptosis.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, E
Dilution	WB~~1:1000 IHC-P~~1:50~100
Images	BCLAF1 Antibody (C-term) (Cat. APR03510G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the BCLAF1 antibody detected the BCLAF1 protein (arrow). BCLAF1 antibody (C-term) (Cat. APR03510G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCLAF1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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