> Antigen, Antibodies, ELISA, Western Blot > Immunoassay Kits > ELISA Kit > Human IL23A/Interleukin-23 subunit alpha ELISA KitBrand |
Leading Biology | Catalog Number |
EK00181E |
Product Type |
ELISA Kit | Field of Research |
Immunology |
Product Overview |
EK00181E is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Interleukin-23 subunit alpha) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Interleukin-23 subunit alpha The ELISA analytical biochemical technique of the EK00181E kit is based on Interleukin-23 subunit alpha antibody-Interleukin-23 subunit alpha antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Interleukin-23 subunit alpha antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Interleukin-23 subunit alpha. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV (%).
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Cellular Localization |
Secreted Secreted upon association with IL12B.
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Assay Type |
Sandwich
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Detection Method |
Spectrophotometrical
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Reactivity |
Human
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Sample Type |
This immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
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Sensitivity |
7.8 pg/mL
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Assay Range |
31.2-2000 pg/mL
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Kit Components |
Assay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
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Other Reagents Required |
Deionized or distilled water
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Gene Name |
IL23A
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MIM |
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UniProt ID |
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Function |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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Form |
ELISA Kits |
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Storage & Stability |
Store at +4°C. Please refer to protocols.
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Applications |
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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Synonyms |
IL-23 subunit alpha,Interleukin-23 subunit p19,IL-23p19,SGRF,UNQ2498/PRO5798
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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