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TRIOBP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25525N-1 50ul / $395
APR25525N-2 100ul / $495
APR25525N-3 200ul / $595

TRIOBP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25525N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRIOBP Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa/68kDa/74kDa/125kDa/243kDa/250kDa/261kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TRIOBP (NP_008963.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Synonyms

TRIOBP; DFNB28; HRIHFB2122; TAP68; TARA; dJ37E16.4; TRIO and F-actin-binding protein

Images

Western blot analysis of extracts of various cell lines, using TRIOBP antibody.

Specification

Quantity

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