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DYNLT1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25421N-1 50ul / $395
APR25421N-2 100ul / $495
APR25421N-3 200ul / $595

DYNLT1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25421N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DYNLT1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 12kDa Observed MW: 13kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DYNLT1 (NP_006510.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

DYNLT1; CW-1; TCTEL1; tctex-1; dynein light chain Tctex-type 1

Images

Western blot analysis of extracts of various cell lines, using DYNLT1 antibody.

Specification

Quantity

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