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KRT81 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25361N-1 50ul / $395
APR25361N-2 100ul / $495
APR25361N-3 200ul / $595

KRT81 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25361N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KRT81 Polyclonal Antibody.

Molecular Weight

Calculated MW: 54kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human KRT81 (NP_002272.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

Synonyms

KRT81; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1; keratin 81

Images

Western blot analysis of extracts of various cell lines, using KRT81 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using KRT81 antibody.

Immunohistochemistry of paraffin-embedded human mammary cancer using KRT81 antibody.

Specification

Quantity

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