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NOS1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19406N-1 50ul / $395
APR19406N-2 100ul / $495
APR19406N-3 200ul / $595

NOS1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19406N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NOS1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 43kDa/125kDa/148kDa/160kDa/164kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NOS1 (NP_000611.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:20 - 1:50

Product Description

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Synonyms

NOS1; IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS; nitric oxide synthase 1

Images

Western blot analysis of extracts of Rat brain, using NOS1 antibody.

Immunofluorescence analysis of HeLa cells using NOS1 antibody.

Specification

Quantity

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