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GAR1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19367N-1 50ul / $395
APR19367N-2 100ul / $495
APR19367N-3 200ul / $595

GAR1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19367N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GAR1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/22kDa Observed MW: 28kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human GAR1 (NP_061856.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.

Synonyms

GAR1; NOLA1; GAR1 ribonucleoprotein

Images

Western blot analysis of extracts of various cell lines, using GAR1 antibody.

Specification

Quantity

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