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TrkB Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18719N-1 50ul / $395
APR18719N-2 100ul / $495
APR18719N-3 200ul / $595

TrkB Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18719N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TrkB Polyclonal Antibody.

Molecular Weight

Calculated MW: 35kDa/53kDa/59kDa/60kDa/81kDa/91kDa/93kDa Observed MW: 110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TrkB (NP_001007098.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Synonyms

NTRK2; GP145-TrkB; TRKB; trk-B; OBHD; BDNF/NT-3 growth factors receptor

Images

Western blot analysis of extracts of various cell lines, using TrkB Antibody.

Immunohistochemistry of paraffin-embedded human lung cancer using TrkB antibody.

Immunohistochemistry of paraffin-embedded human placenta using TrkB antibody.

Specification

Quantity

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