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SEC61B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22365N-1 50ul / $395
APR22365N-2 100ul / $495
APR22365N-3 200ul / $595

SEC61B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22365N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SEC61B Polyclonal Antibody.

Molecular Weight

Calculated MW: 9kDa Observed MW: 12kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human SEC61B (NP_006799.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

Synonyms

SEC61B; Sec61 translocon beta subunit

Images

Western blot analysis of extracts of various cell lines, using SEC61B antibody.

Specification

Quantity

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