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SNRPN Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22299N-1 50ul / $395
APR22299N-2 100ul / $495
APR22299N-3 200ul / $595

SNRPN Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22299N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNRPN Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa/25kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human SNRPN (NP_003088.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.

Synonyms

SNRPN; HCERN3; PWCR; RT-LI; SM-D; SMN; SNRNP-N; SNURF-SNRPN; sm-N; PWS; small nuclear ribonucleoprotein polypeptide N

Images

Western blot analysis of extracts of various cell lines, using SNRPN antibody.

Specification

Quantity

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