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IL6R Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22271N-1 50ul / $395
APR22271N-2 100ul / $495
APR22271N-3 200ul / $595

IL6R Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22271N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL6R Polyclonal Antibody.

Molecular Weight

Calculated MW: 40kDa/51kDa Observed MW: 52kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IL6R (NP_000556.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Synonyms

IL6R; CD126; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ; gp80; interleukin 6 receptor

Images

Western blot analysis of extracts of various cell lines, using IL6R antibody.

Specification

Quantity

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