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MMP14 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22262N-1 50ul / $395
APR22262N-2 100ul / $495
APR22262N-3 200ul / $595

MMP14 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22262N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMP14 Polyclonal Antibody.

Molecular Weight

Calculated MW: 65kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human MMP14

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IF

Dilution

IF 1:50 - 1:200

Product Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Synonyms

MMP14; MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS; MT-MMP1; matrix metallopeptidase 14

Images

Immunofluorescence analysis of U2OS cells using MMP14 antibody.

Specification

Quantity

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