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YTHDF2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22185N-1 50ul / $395
APR22185N-2 100ul / $495
APR22185N-3 200ul / $595

YTHDF2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22185N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality YTHDF2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa/62kDa Observed MW: 68kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human YTHDF2 (NP_057342.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Synonyms

YTHDF2; CAHL; HGRG8; NY-REN-2; YTH domain-containing family protein 2

Images

Western blot analysis of extracts of various cell lines, using YTHDF2 antibody.

Specification

Quantity

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