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MYOF Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21989N-1 50ul / $395
APR21989N-2 100ul / $495
APR21989N-3 200ul / $595

MYOF Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21989N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYOF Polyclonal Antibody.

Molecular Weight

Calculated MW: 17kDa/46kDa/49kDa/179kDa/229kDa/233kDa/234kDa Observed MW: 250kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MYOF (NP_038479.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Synonyms

MYOF; FER1L3; myoferlin

Images

Western blot analysis of extracts of various cell lines, using MYOF antibody.

Specification

Quantity

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