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NFAT2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21949N-1 50ul / $395
APR21949N-2 100ul / $495
APR21949N-3 200ul / $595

NFAT2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21949N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>B Cell Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NFAT2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 38kDa/74- 88kDa/100-101kDa Observed MW: 78kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NFAT2 (NP_765978.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:3000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Synonyms

NFATC1; NF-ATC; NF-ATc1.2; NFAT2; NFATc; nuclear factor of activated T-cells 1

Images

Western blot analysis of extracts of various cell lines, using NFAT2 antibody.

Immunohistochemistry of paraffin-embedded human tonsil using NFAT2 antibody.

Specification

Quantity

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