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RNF170 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21751N-1 50ul / $395
APR21751N-2 100ul / $495
APR21751N-3 200ul / $595

RNF170 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21751N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF170 Polyclonal Antibody.

Molecular Weight

Calculated MW: 13kDa/18kDa/20kDa/22kDa/26kDa/29kDa Observed MW: 30kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RNF170 (NP_001153696.1).

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.

Synonyms

RNF170; ADSA; SNAX1; ring finger protein 170

Images

Western blot analysis of extracts of various cell lines, using RNF170 antibody.

Specification

Quantity

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