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PRR5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21724N-1 50ul / $395
APR21724N-2 100ul / $495
APR21724N-3 200ul / $595

PRR5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21724N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Autophagy

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRR5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/32kDa/41kDa/42kDa/45kDa Observed MW: 53kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PRR5 (NP_851850.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

Synonyms

PRR5; FLJ20185k; PP610; PROTOR-1; PROTOR1; proline rich 5

Images

Western blot analysis of extracts of various cell lines, using PRR5 antibody.

Immunofluorescence analysis of C6 cells using PRR5 antibody.

Specification

Quantity

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