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HBG1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21541N-1 50ul / $395
APR21541N-2 100ul / $495
APR21541N-3 200ul / $595

HBG1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21541N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HBG1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa Observed MW: 12kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human HBG1 (NP_000550.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200

Product Description

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Synonyms

HBG1; HBG-T2; HBGA; HBGR; HSGGL1; PRO2979; hemoglobin subunit gamma-1

Images

Western blot analysis of extracts of various cell lines, using HBG1 antibody.

Specification

Quantity

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