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HERC5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21441N-1 50ul / $395
APR21441N-2 100ul / $495
APR21441N-3 200ul / $595

HERC5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21441N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HERC5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 116kDa Observed MW: 117kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HERC5 (NP_057407.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Synonyms

HERC5; CEB1; CEBP1; E3 ISG15--protein ligase HERC5

Images

Western blot analysis of extracts of various cell lines, using HERC5 antibody.

Specification

Quantity

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